Experiments involving the deliberate formation of recombinant or synthetic nucleic acid molecules containing genes for the biosynthesis of toxin molecules lethal for vertebrates at an LD50 of less than 100 nanograms per kilogram of body weight (see Section III-B of the NIH Guidelines)
The deliberate transfer of a drug resistance trait to a microorganism when such resistance could compromise the ability to control the disease agent in humans, veterinary medicine, or agriculture (see Section III-A-1-a of the NIH Guidelines)
Guidelines for handling human material52 (Clinical BRF Guide)
Animal Experiments
Stem Cell Information
Incident Reporting
Dual Use of Research Concern Guidance (DURC)